Генетические аспекты агрессивного поведения у больных шизофренией (аналитический обзор)

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Мустафина Т., Леопольд А.В., Павлов К.А., Кекелидзе З.И., Макушкин Е.В., Фастовцов Г.А., Чехонин В.П. Генетические аспекты агрессивного поведения у больных шизофренией (аналитический обзор) // Российский психиатрический журнал. 2014. №3. С. 67-78.

Аннотация

В статье представлен обзор литературы по вопросу доказательных исследований в психиатрии и практической ценности получаемых в них результатов. Осуществленный анализ позволяет сделать вывод о том, что современные методы молекулярной биологии предоставляют новые инструменты описания и анализа ассоциации ряда однонуклеотидных полиморфизмов с агрессивным поведением у больных шизофренией, что может использоваться при разработке комплексных критериев определения генетического риска у носителей предрасполагающего генотипа полиморфных маркеров для выбора оптимальной психокоррекционной стратегии.

Ключевые слова генетика; гены; агрессия; шизофрения; однонуклеотидные полиморфизмы

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