Психотическая депрессия с позиции персонифицированного подхода
Рекомендуемое оформление библиографической ссылки:
Петрова Н.Н., Столяров А.Р. Психотическая депрессия с позиции персонифицированного подхода // Российский психиатрический журнал. 2021. №1. С. 82-92.
В научном обзоре с целью всестороннего освещения и концептуализации психотической депрессии проведён систематический обзор литературы, описаны потенциальные биохимические, нейровизуализационные, генетические и патофизиологические биомаркёры психотической депрессии, а также психофармакологические и немедикаментозные подходы к её лечению. Выполнен сравнительный анализ психотической и непсихотической депрессии, депрессии в структуре шизофрении, биполярной депрессии. Рассмотрено место психотической депрессии в действующих классификациях психических расстройств – МКБ-10 и DSM-5, а также в свете перехода на МКБ-11. Делается вывод о том, что, несмотря на ряд серьёзных оснований, позволяющих рассматривать психотическую депрессию как отдельное заболевание, вопрос остаётся открытым.
Ключевые слова психотическая депрессия; распространённость; систематизация; клиническая характеристика; биомаркёры; лечение
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DOI: http://dx.doi.org/10.47877/1560-957Х-2021-10109
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