Субъективный компонент терапевтического действия психофармакологических препаратов

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Метлина М.В., Дорофеева О.А. Субъективный компонент терапевтического действия психофармакологических препаратов // Российский психиатрический журнал. 2022. №5. С. 39-50.

Аннотация

В научном обзоре с целью расширения представлений о субъективном компоненте терапевтического действия психофармакологических препаратов представлены обобщающие данные о феномене и структуре субъективного фактора, физиологических и нейробиологических основах его формирования. Показана его связь с объективными характеристиками фармакологического действия, а также возможности практического применения субъективной оценки в клинической практике. Приведённые данные свидетельствуют об актуальности и высокой значимости субъективного фактора в реализации действия психофармакологических средств. Исследования в этой области позволят выявить дополнительные индивидуальные эффекты у психофармакологических препаратов и особенности их клинико-фармакологического действия, что расширит возможности персонифицированного подхода в терапии психических расстройств.

Ключевые слова субъективная оценка; терапевтическое действие; психофармакологические препараты; интероцептивные эффекты; плацебо-эффект; эффективность терапии; персонализированный подход

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DOI: http://dx.doi.org/10.47877/1560-957Х-2022-10504

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