Dynamics of functional interaction of neurocognitive domains in the progressive course of the epileptic process
Suggested citation:
Lavrushchik MV, Zeyger MV, Kornilova SV, et al. [Dynamics of functional interaction of neurocognitive domains in the progressive course of the epileptic process]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2023;(3):32-40. Russian
In this cross-sectional retrospective study pursuing the objective of studying the dynamics of functional interaction of neurocognitive domains during the progressive course of the epileptic process using the Addenbrooke’s Cognitive Examination (III), an analysis of the structure of attention, speech, memory and visual-spatial functions domains and their subdomains was carried out, correlation matrices of their interaction were built and peculiarities of interaction were revealed depending on the degree of severity (mild, moderate, severe) of cognitive impairment. An increase in the extent and intensity of damage to neuropsychological functions is shown as the epileptic process progresses – an increase in the representation of both the number of subdomains and the volume of their involvement in reciprocal inhibitory processes.
Keywords epilepsy; neurocognitive domains and subdomains; Addenbrooke’s Cognitive Examination
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