The role of impairment of predictive coding mechanisms in the genesis of psychopathology in schizophrenia

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Rabinovich EI, Telesheva KYu. [The role of impairment of predictive coding mechanisms in the genesis of psychopathology in schizophrenia]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2024;(1):78-86. Russian

Abstract

In this scientific review, in order to systematize ideas about the relationship between impairment of the mechanisms of predictive coding and development of certain symptoms and psychopathological states in schizophrenia, we have carried out the critical analysis of existing theoretical and empirical studies. Predictive coding mechanisms underlie the functioning of almost all mental processes and explain the phenomena of anticipation, which is one of the most important regulatory mechanisms in human activity. Violation of the anticipation process can act as the main link in the development of various psychopathological processes. This makes it relevant to search for the psychophysiological foundations of predictive coding for understanding the pathogenesis of pathological conditions and creating approaches to their assessment and correction. The results of the theoretical study allow us to interpret the symptoms of schizophrenia based on the theory of predictive coding, and identify patterns in their development. In conclusion, we argue the validity of the theory of predictive coding as a theoretical and methodological basis for studying the mechanisms of the pathogenesis of mental disorders.

Keywords prediction; anticipation; schizophrenia; hallucinations; delusions; agency

References

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