Neurocognitive disorders in schizophrenia patients with alcohol dependence syndrome
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Galkin SA, Kornetova EG, Kornetov AN, et al. [Neurocognitive disorders in schizophrenia patients with alcohol dependence syndrome]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2025;(2):48-54. Russian
In this empirical study looking at the indicators of cognitive functioning in patients with schizophrenia with alcohol dependence syndrome and without comorbid alcohol pathology, 274 patients were examined. The scale of brief assessment of cognitive functions in patients with schizophrenia (BACS) was used to identify neurocognitive deficits. About a quarter (25.2%) of the cases were represented by patients with schizophrenia with a clinical picture of formed alcoholism. Patients with comorbid pathology coped significantly worse with tasks such as “Digit sequencing”, “Verbal fluency”, “Symbol coding” and “Tower of London” (p<0.05). Also, the analysis using the criterion χ2 showed statistically significant differences in the frequency of occurrence of the degree of severity of neurocognitive deficiency between groups of patients with schizophrenia with and without comorbid pathology (p=0.016).
Keywords schizophrenia; comorbidity; alcohol dependence; neurocognitive deficit; working memory; semantic fluency; attention; executive functions
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