EEG-derived biomarkers of military posttraumatic stress disorder: resting state and auditory P50 sensory gating

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Telesheva KYu, Zakurazhnaya VI, Morozova IO, et al. [EEG-derived biomarkers of military posttraumatic stress disorder: resting state and auditory P50 sensory gating]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2024;(6):44-57. Russian

Abstract

The research involved 42 veterans with PTSD against a control group of 46 men without PTSD or traumatic events in their history and with no experience of combat. EEG recording included eyes-closed resting state, and suppression of the P50 potential. We examined the EEG power spectrum, the alpha asymmetry, the amplitude and latency of the P50 potential, and the sensory gating. The results show higher theta (5–7 Hz), beta-1 (14–20 Hz) and beta-2 (21–32 Hz) in PTSD. No significant differences in alpha asymmetry were found. A lower amplitude in the first stimulus of the P50 was identified. However, no significant differences in the suppression of the P50 potential were found.

Keywords EEG; power spectrum; frontal alpha-asymmetry; sensory gating; combatants; posttraumatic stress

References

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