Predictors of the therapeutic dynamics of cognitive impairment in nonpsychotic depressive disorders
Suggested citation:
Fedorova AI, Akhapkin RV, Fayzulloev AZ. [Predictors of the therapeutic dynamics of cognitive impairment in nonpsychotic depressive disorders]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2019;(1):47-57. Russian
In this scientific review, pursuing the goal of analyzing the Russian and foreign publications dealing with the peculiarities of the therapeutic dynamics of cognitive impairment in unipolar depressive disorders, we had studied over 250 sources, 60 of which have been included in this review. We have demonstrated that the symptoms of cognitive impairment do persist in worsening patients’ social functioning, in spite of their treatment with antidepressants and their syndromic remission. We submit the description of the probable predictors of therapeutic dynamics of cognitive impairment, which follow the regular pattern of their own, different from that of the affective disorders. This determines the novelty of our work and the strategy for carrying out further research of the predictors of cognitive impairment for purposes of optimizing the choice of adequate therapy for this particular cohort of patients.
Keywords depression; cognitive impairment; antidepressants; dynamics of cognitive impairment; predictors of cognitive impairment
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DOI: http://dx.doi.org/10.24411/1560-957X-2019-11907
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