Interdisciplinary studies of anxiety-depressive spectrum disorders in systemic lupus erythematosus patients

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Borisova AB, Reshetnyak TM, Lisicyna TA, et al. [Interdisciplinary studies of anxiety-depressive spectrum disorders in systemic lupus erythematosus patients]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2020;(1):42-48. Russian

Abstract

In this scientific review we pursue the objective of studying the general pathogenetic, clinical-dynamic, prognostic and therapeutic aspects in the field of psychiatry and rheumatology. We identify the negative impact of mental disorders, above all – that of depression, on triggering, clinical manifestations, prognosis, and treatment of systemic lupus erythematosus, as well as the undoubtedly triggering and chronic impact of severe immune inflammatory pathology on anxiety and depressive disorders. In this regard, systemic lupus erythematosus and anxiety-depressive spectrum disorders patients have a lower quality and expectancy of life than patients with no mental pathology.

Keywords systemic lupus erythematosus; anxiety-depressive spectrum; mental disorders; cognitive impairment; inflammation; stress factors; pathogenesis; therapy

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DOI: http://dx.doi.org/10.24411/1560-957X-2020-12004

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