Attenuated psychotic symptoms in the structure of youth depression (clinical and psychopathological aspects)
Suggested citation:
Rumyancev AO, Omel'chenko MA, Kaleda VG. [Attenuated psychotic symptoms in the structure of youth depression (clinical and psychopathological aspects)]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2018;(1):61-70. Russian
For definition of psychopathological features, patterns of current and criteria of the forecast of juvenile depressions with attenuated psychotic symptoms it was carried out an observational study. The research included 140 patients who made two groups. The clinical group made 84 patients of youthful age (16–25 years) first hospitalized for nonpsychotic mental disorders that occur with a depressive episode, having in its structure attenuating psychotic symptoms. The follow-up group of the patients hospitalized earlier with a similar state has made 56 patients, duration of follow-up was at least 5 years. Applied clinical- psychopathological, clinicalfollow-up and psychometric methods. It has been established that attenuated psychotic symptoms in a selected clinical type has a significant pathoplastic impact on disease course for patients with juvenile depression, with different combinations of affective and psychotic symptoms in remission, social and employment status, the probability of the manifestation of psychosis and outcome.
Keywords attenuated; psychosis; symptoms; depression; mental disorders
1. Kaleda VG Zakonomernosti techeniya i iskhoda pristupoobraznykh endogennykh psikhozov, manifestiruyushchikh v yunosheskom vozraste (katamnesticheskoe issledovanie) [Endogenous psychoses with a first episode at the juvenile age: course and outcome (follow-up study)]. Zh Nevrol Psikhiatr Im SS Korsakova. 2008;108(9):11–23. Russian. 2. Tiganov AS. Shizofreniya. In: Ed. by AS Tiganov Psikhiatriya. Rukovodstvo dlya vrachei. Moscow; 2012. Vol 1. p. 443–73. Russian. 3. Tsutsul'kovskaya MYa, Panteleeva GP. Klinika i differentsial'naya otsenka nekotorykh psikhopatologicheskikh sindromov pubertatnogo vozrasta. In: Problemy shizofrenii detskogo i podrostkovogo vozrasta. Moscow; 1986. p.13–28. Russian. 4. Lemos-Giraldez S, Vallina-Fernandez O, Fernandez-Iglesias P, Vallejo-Seco G, Fonseca-Pedrero E, Paino-Pieiro M, et al. Symptomatic and functional outcome in youth at ultra-high risk for psychosis: A longitudinal study. Schizophr Res. 2009;115:121–9. 5. McGorry P, Nordentoft M, Simonsen E. Introduction to "Early psychosis: a bridge to the future". Br J Psychiatry Suppl. 2005;48:1–3. 6. Krylova ES. Kliniko-psikhopatologicheskie aspekty yunosheskikh depressii s kartinoi «metafizicheskoi intoksikatsii». Psikhiatriya. 2003;6(06):29–35. Russian. 7. Oleichik IV. Psikhopatologiya, tipologiya i nozologicheskaya otsenka yunosheskikh endogennykh depressii (kliniko-katamnesticheskoe issledovanie). Zh Nevrol Psikhiatr Im SS Korsakova. 2011;(2):10–9. Russian. 8. Rohde P. Adolescent Depression: Treatment. In: The international encyclopedia of depression. New York: Ingram Springer; 2009. p. 4–13. 9. Tsapakis EM, Soldani F, Tondo L, Baldessarini RJ. Efficacy of antidepressants in juvenile depression: meta-analysis. The British Journal of Psychiatry. 2008;193(1):10–7. 10. Rushton JL, Forcier M, Schectman RM. Epidemiology of Depressive Symptoms in the National Longitudinal Study of Adolescent Health. J. Am. Acad. Child. Adolescent. Psychiatry. 2002;41(2):1147–56. 11. Weissman MM, Wolk S, Goldstein RB, et al. Depressed adolescents grown up. JAMA. Psych. Neurol. 1999;281:1707–13. 12. Wigman J, van Nierop M, Vollebergh W, Lieb R, Beesdo-Baum K, Wittchen H, van Os J. Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity -implications for diagnosis and ultra-high risk research. Schizophr Bull. 2012;38(2):247–57. doi: 10.1093/schbul/ sbr196. Epub 2012 Jan 18. 13. Schimmelmann B, Michel C, Schaffner N, Schultze-Lutter F. What percentage of people in the general population satisfies the current clinical at-risk criteria of psychosis? Schizophr Res. 2011;125(1): 99–100. doi:10.1016/j.schres.2010.09.018 14. Schimmelmann B, Walgner P, Schultze-Lutter F. The significance of at-risk symptoms of psychosis in children and adolescents. Can J Psychiatry. 2013;58(1):32–40. 15. Skugarevskaya MM, Sindrom oslablennogo psikhoza – novyi diagnoz v psikhiatrii? Psikhiatriya i psikhofarmakoterapiya. 2014;16(2):40–3. Russian. 16. McGorry PD, Yung A, Phillips L. Ethics and early intervention in psychosis: keeping up the pace and staying in step. Schizophr Res. 2001;51:17–29. 17. Miller TJ, McGlashan TH, Woods SW, et al. Symptom assessment in schizophrenic prodromal states. Psychiatr Q. 1999;70(4):273–87. 18. Kaymaz N, Drukker M, Lieb R, Wittchen H.-U, Werbeloff N, Weiser M, Lataster T, Van Os J. Do subthreshold psychotic experiences predict clinical outcomes in unselected non-help-seeking populations-based samples? A systematic review and meta-analyses, enriched with new results. Psychological Medicine. 2012;42(11):2239–53. 19. Schultze-Lutter F. Prediction and Early Detection of First-Episode Psychosis Handbook of Schizophrenia Spectrum Disorders. 2007;II: 207–67. 20. Andrienko EV, Platonova TP, Tiganov AS. Nekotorye vidy domanifestnykh rasstroistv pri pristupoobrazno-progredientnoi shizofrenii. Zh Nevrol Psikhiatr Im SS Korsakova. 2014;(12):31–5. doi:10.17116/jnevro201411412131-35. Russian. 21. Kaleda VG, Mezentseva OE, Krylova ES, Barkhatova AN. Osobennosti domanifestnogo etapa endogennogo psikhoza s pervym pristupom v yunosheskom vozraste. Zh Nevrol Psikhiatr Im SS Korsakova. 2012;112(5):22–8. Russian. 22. Cannon TD, Cadenhead K, Cornblatt B, et al. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry. 2008;65:28–37. 23. Fusar-Poli P, Deste G, Smieskova R, Barlati S, Yung AR, Howes O, et al. Cognitive functioning in prodromal psychosis: a metaanalysis. Arch Gen Psychiatry. 2012;69(6):562–71. doi:10.1001/ archgenpsychiatry.2011.1592. 24. Woodberry KA, Shapiro DI, Bryant C, Seidman LJ. Progress and Future Direction in Research on the Psychosis Prodrome: A Riview for Clinicias. Harvard Review of Psychiatry. 2016;24(2). 25. Ziermans T, Schothorst P, Sprong M, van Engeland H. Transition and remission in adolescents at ultra-high risk for psychosis. Schizophr Res. 2011;126(1-3):58–64. doi:10.1016/j.schres.2010.10.022. 26. Morrison AP, French P, Parker S, Roberts M, Stevens H, Bentall RP, et al. Three Year Follow-up of a Randomized Controlled Trial of Cognitive Therapy for the Prevention of Psychosis in People at Ultrahigh Risk. Schizophrenia Bulletin 2007:33(3);682–7. 27. McGlashan TH, Miller TJ, Woods SW. Pre-onset detection and intervention research in schizophrenia psychoses: current estimates of benefit and risk. Schizophr. Bull. 2001;27:563–70. 28. Mastrigt S, Addington J. Assessment of premorbid function in the firstepisode schizophrenia: modifications to the Premorbid Adjustment Scale. J Psychiatry Neurosci. 2002;27(2):92–110. 29. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psych. 1968;6:278–96.
DOI: http://dx.doi.org/10.24411/1560-957X-2018-1%25x
Article Metrics
Metrics powered by PLOS ALM