Peculiarities of Psychopathological Symptoms in Patients with Schizophrenia and Patients with Schizoaffective Disorder Infected with Human Immunodeficiency Virus
Suggested citation:
Polyanskiy DA, Kalinin VV. [Peculiarities of Psychopathological Symptoms in Patients with Schizophrenia and Patients with Schizoaffective Disorder Infected with Human Immunodeficiency Virus]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2018;(4):31-39. Russian
This observational study, pursuing the goal of investigating the psychopathological symptoms and
the cognitive functions in schizophrenic patients and those with schizoaffective disorder and HIV, has looked for significant differences in symptom severity between the above-said groups. We have used the quantified clinical-psychopathological and the flow cytometry methods. We have found antagonistic relationships between HIV and schizophrenia, and the schizoaffective disorder, which result in diminished severity of psychopathological symptoms. HIV makes an impact on the course of the cognitive processes in that it somewhat «loosens» the symptom complexes, which are persistently found in schizophrenia and schizoaffective disorder, also altering their structure.
Keywords schizophrenia; HIV infection; psychopathological syndromes
1. VICh-infektsiya i SPID. Natsional'noe rukovodstvo, kratkoe izdanie. Pod red. akad. RAN VV Pokrovskogo. Moscow; 2014. 518 p. Russian. 2. Pokrovskiy VV. Epidemiologiya i profilaktika VICh-infektsii i SPID. Moscow; 1996. 436 p. Russian. 3. Daruna JH. Introduction to Psychoneuroimmunology. Amsterdam (Netherlands): Academic Press, Elsevier; 2004. 280 p. 4. David AS, Fleminger S, Kopelman MD, et al. Lishman’s organic psychiatry: a textbook of neuropsychiatry. 4th Ed. Chichester, W.Sussex, UK: John Willey-Blackwell. 2009;2(7):397–472. 5. Lyketsos CG, Hanson AL, Fishman M, et al. Screening for Psychiatric Morbidity in a Medical Outpatient Clinic for HIV Infection: The Need for a Psychiatric Presence. The International Journal of Psychiatry in Medicine. 1994;24(2):103–13. 6. Dunbar N, Brew BJ. Neuropsychological dysfunction in HIV infection. Journal of Neuro-AIDS. 1996;1(3):73–102. DOI: 10.1300/j128v01n03_05. 7. Sidtis JJ, Price RW. Early HIV-1 infection and the AIDS dementia complex. Neurology. 1990;40(2):323. DOI: 10.1212/wnl.40.2.323. 8. Dilley MD, Fleminger S. Intracranial Infections. David AS, Fleminger S, Kopelman MD, et al. Lishman’s organic psychiatry: a textbook of neuropsychiatry. 4th Ed. A John Willey & Sons Ltd, Chichester, West Sussex, UK: Willey-Blackwell. 2009;2(7):414–8. DOI:10.1002/9781444316803. 9. Fernandez F. Neuropsychiatric aspects of human immunodeficiency virus (HIV) infection. Current Psychiatry Reports. 2002;4(3):228–31. DOI: 10.1017/cbo9780511543975.021. 10. Foster R, Everall I. HIV and AIDS. Chapter published in Lloyd G, Elspeth Guthrie E. Handbook of Liaison Psychiatry. Cambridge University Press; 2007. p. 474–505. DOI: 10.1017/cbo9780511543975.021. 11. King MB. AIDS, HIV and Mental Health. Journal Article in Psychological Medicine. Cambridge University Press. 1994;24(2):533. DOI: 10.1017/S0033291700027616. 12. Treisman GJ, Angelino AF, Hutton HE. Psychiatric Issues in the Management of Patients With HIV Infection. Journal of the American Medical Association. 2001;286(22):2857. DOI: 10.1001/jama.286.22.2857. 13. Sewell DD, Jeste DV, McAdams LA, et al. HIV-associated psychosis: a study of 20 cases. San Diego HIV Neurobehavioral Research Center Group. American Journal of Psychiatry. 1994;151(2):237–42. DOI: 10.1038/sj.npp.1380208. 14. Sewell D. Schizophrenia and HIV. Schizophrenia Bulletin. 1996;22(3):465–73. DOI: 10.1093/schbul/22.3.465. 15. Querques J, Freudenreich O. Psychiatric aspects of HIV infection and AIDS. In Massachusetts General Hospital. Comprehensive Clinical Psychiatry. Stern TA, Fava M, Wilens TE, et al. 2th Ed. Elsevier. 2016;(57):631. 16. Sidtis JJ, Price RW. Early HIV-1 infection and the AIDS dementia complex. Neurology. 1990;40(2):323. DOI: 10.1212/wnl.40.2.323. 17. Clifford DB. Human Immunodeficiency Virus-Associated Dementia. Archives of Neurology. 2000;57(3):321–4. DOI: 10.1001/archneur.57.3.321. 18. Antinori A, Arendt G, Becker JT, et al. Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 2007;69(18):1789–99. DOI:10.1212/01.wnl.0000287431.88658.8b. 19. McArthur JC. HIV dementia: an evolving disease. Journal of Neuroimmunology. 2004;157(1–2):3–10. DOI: 10.1016/j.jneuroim.2004.08.042. 20. Brew BJ, Pemberton L, Cunningham P, et al. Levels of Human Immunodeficiency Virus Type 1 RNA in Cerebrospinal Fluid Correlate with AIDS Dementia Stage. The Journal of Infectious Diseases. 1997;175(4):963–6. DOI: 10.1086/514001. 21. Fernandez F. Neuropsychiatric aspects of human immunodeficiency virus (HIV) infection. Current Psychiatry Reports. 2002;4(3):228–31. DOI: 10.1007/s11920-002-0034-5. 22. Yiannoutsos CT, Ernst T, Chang L, et al. Regional patterns of brain metabolites in AIDS dementia complex. NeuroImage. 2004;23(3):928–35. DOI: 10.1016/j.neuroimage.2004.07.033. 23. Bell JE, Brettle RP, Chiswick A, et al. HIV encephalitis, proviral load and dementia in drug users and homosexuals with AIDS. Effect of neocortical involvement. Brain. 1998;121(11):2043–52. DOI: 10.1093/brain/121.11.2043. 24. Brew BJ. AIDS dementia complex. Chapter in Handbook of Clinical Neurology; 2007. p. 79–91. DOI:10.1016/s0072-9752(07)85006-8. 25. Jendogennye psihicheskie rasstrojstva. Shizofrenija. Psihiatrija: Rukovodstvo dlja vrachej. Pod red. AS Tiganova. Moscow. 2012;(1):443–55. Russian. 26. Mosolov SN. SHkaly psihometricheskoj ocenki simptomatiki shizofrenii i koncepciya pozitivnyh i negativnyh rasstrojstv. Moscow, 2001; 238 p. 27. Kim Dzh-O, Mjuller ChU. Faktornyj analiz: statisticheskie metody i prakticheskie voprosy. Faktornyj, diskriminantnyj i klasternyj analiz. Pod red. IS Enjukova. Moscow, 1989; 215 p. Russian.
DOI: http://dx.doi.org/10.24411/1560-957X-2018-1%25x
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