Inhibitory control and its effect on the treatment of patients with affective disorders
Suggested citation:
Galkin SA, Vasil'eva SN, Ivanova SA, et al. [Inhibitory control and its effect on the treatment of patients with affective disorders]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2020;(4):71-76. Russian
In an empirical study, 67 patients with affective disorders and 30 mentally and somatically healthy individuals were examined using the Go/Nogo task in order to identify the features of inhibitory control in patients with affective disorders, as well as to assess its impact on the therapeutic response. The effectiveness of therapy for affective disorders was evaluated using the CGI-i scale. The results of the study showed significant impairment of executive functioning in the form of the deficit of inhibitory control in patients with affective disorders compared to healthy controls. We have also found the significant effect of inhibitor control deficits on therapy: patients who did not respond to therapy made statistically significantly higher number of errors in the Go/Nogo task.
Keywords affective disorders; prognosis; therapy; inhibitory control; Go/Nogo task
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DOI: http://dx.doi.org/10.24411/1560-957Х-2020-10409
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