Facial affect recognition in patients with schizophrenia and schizoaffective disorder: Alterations of P100 and N170
Suggested citation:
Spektor VA, Mnacakanyan EV, Shmukler AB. [Facial affect recognition in patients with schizophrenia and schizoaffective disorder: Alterations of P100 and N170]. Rossiiskii psikhiatricheskii zhurnal [Russian Journal of Psychiatry]. 2020;(6):82-92. Russian
This pilot study presents analysis of ERPs in 16 healthy controls, 10 patients with schizophrenia and 8 patients with schizoaffective disorder. Patients with schizophrenia showed P100 and N170 latencies decrease to all facial expressions (fear, neutral, happiness). Patients with schizoaffective disorder demonstrated minimal latencies to these stimuli and healthy controls results were in intermediate position between patient groups. In schizoaffective disorder group positive correlation was found between positive PANSS score and both peaks latencies. If the differences between the patient groups are confirmed in larger sample than they may be used as a marker for differential diagnostics.
Keywords schizophrenia; schizoaffective disorder; facial affect recognition; event related potentials; P100; N170
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DOI: http://dx.doi.org/10.24411/1560-957Х-2020-10610
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