Нейротрофический фактор мозга как потенциальный диагностический биомаркер психических расстройств
Рекомендуемое оформление библиографической ссылки:
Павлова О.В., Гурина О.И., Шпорт С.В., Павлов К.А. Нейротрофический фактор мозга как потенциальный диагностический биомаркер психических расстройств // Российский психиатрический журнал. 2023. №2. С. 76-85.
В научном обзоре с целью исследования возможности использования уровней нейротрофического фактора мозга в периферической крови в качестве диагностического биомаркера психических заболеваний, в том числе депрессивных расстройств, проведен анализ российских и зарубежных публикаций, связанных с данной темой. Уделено внимание синтезу нейротрофического фактора мозга и его регуляции в центральной нервной системе, функциональному значению данного белка, определены его источники в периферической крови, а также выявлены корреляции содержания этого белка в центральной нервной системе и на периферии.
Ключевые слова психические расстройства; биомаркер; нейротрофический фактор мозга; BDNF; корреляция центрального и периферического уровней BDNF
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